This original research was presented by Research team at Jothydev’s Diabetes Research Centre headed by Dr.Jothydev Kesavadev at the 7th International Conference of Advanced Technologies & Treatments (ATTD) at Vienna, Austria.

Glycemic excursions in pre-diabetes are seldom evaluated in clinical practice. We assessed clinical utility of CGM in pre-diabetes and its impact on modifying lifestyles to prevent diabetes.

6 patients were enrolled in 3 month study via convenience sampling based on ability and willingness to follow instructions. Mean age 48.5 yrs, mean BMI 26.73 kg/m2. Measured blood glucose were <126 mg/dl during fasting and <150 mg/dl post breakfast. CGM was performed using iPro2 recorder at 0 and 3 months(5-7 days).Advice on lifestyle modifications were repeated once in 2 weeks by a multi-disciplinary team of doctors, dietitians, pharmacist, nurse educators, device technician, psychologist etc. who made detailed analyses of CGM recordings.

Trends observed in CGM at month 0 included hyperglycemic spikes 30- 90 mins after breakfast and dinner and glycemic variability missed in usual SMBG. At 3 months, CGM revealed smooth curves with average weight reduction of 2.35 kgs.(Table) CGM may prove an excellent tool to unravel glycemic excursions most often missed in SMBG in pre-diabetes patients. CGM could evolve as motivational tool in pre-diabetes patients to prevent progression to overt diabetes.

CGM Parameters (n =6)	Mean (mg/dl) (0 month)	Standard deviation (0 month)	Mean (mg/dl) (3 months)	Standard deviation (3 months)
FBS	110.8	20.77	91	6.42
HbA1c	5.9%	0.38	5.4%	0.28
No: of High Excursion	7.2	5.23	2.2	2.14
No: of Low Excursion	2.8	3.82	1.5	1.52
Highest Sensor Value	178.2	28.99	151.5	6.44
Lowest Sensor Value	66	12.33	73.8	3.06
Duration within 70-40 mg/dl	89.7	9.27	96.3	2.73