This January marks 102 years since the first successful administration of insulin to Leonard Thompson, a 14-year-old boy suffering from type 1 diabetes. These historic records from Toronto General Hospital chronicle a pivotal moment in medical history when insulin, termed "Macleod serum," was administered on January 11, 1922. Although the first dose yielded modest results, a refined preparation administered on January 23 produced a dramatic improvement, effectively saving Thompson's life.

The handwritten medical notes document his diagnosis, deteriorating condition, and the first ever insulin injection, followed by remarkable recovery milestones. The accompanying chart vividly illustrates the drastic reduction in urine glucose levels, a testament to insulin's life-saving impact. Prior to insulin's discovery, type 1 diabetes was universally fatal, with patients succumbing to severe malnutrition or diabetic ketoacidosis. This breakthrough, achieved by Frederick Banting, Charles Best, John Macleod, and James Collip, ushered in a new era in diabetes management, offering hope to millions worldwide.

As we reflect on this incredible achievement, it is awe-inspiring to see how far we've come in the past 102 years, from Leonard Thompson’s lifesaving injections to today’s advanced therapies like continuous glucose monitors and automated insulin delivery systems. This milestone serves as a reminder of the power of innovation and collaboration in medicine, inspiring ongoing advancements in diabetes care.