This original research from Jothydev’s Diabetes Research Centre was presented by Dr.Jothydev Kesavadev at the 74th American Diabetes Association Scientific Sessions at San Francisco, California.

Benefits of intensive glycemic control in preventing vascular complications of diabetes & as a cost effective modality is largely offset by episodes/fear of hypoglycemia with fatal consequences. Despite limitations & higher costs, CGM detects glucose trends not revealed by SMBG. We analysed data of 432 T2D (male 243, female 189), aged 52.2 (15.04) on professional CGM over 6-7 days in past 1 year. CGM revealed low glucose trends undetected with 4 point SMBG. Nocturnal hypoglycemia (11.86%), hypoglycemia unawareness (10.32%) & Somogyi (2.50%) were detected in CGM. Therapeutic & lifestyle modifications were carried out (Table 1) & A1c reassessed (Table 2). After therapeutic and lifestyle modifications post CGM, hypoglycemic episodes were reduced- hypoglycemia (2.48%), hypoglycemia unawareness (3.76%) & Somogyi (0.20%). Cost effectiveness was analysed as incremental Cost/QALY gained.

CGM was projected to reduce lifetime probability of hypoglycemic episodes & may be recommended as routine in T2D to achieve safe A1c targets with confidence.

Table 1

Table 2