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Welcome to the January Issue of GEMS!

    As the New Year begins, it brings renewed focus on prevention, reflection, and long-term health. January is a natural moment to reset priorities, and in diabetes care, it reinforces the importance of early action, sustained lifestyle change, and integrated management across the lifespan.

    This edition of GEMS explores the wider forces shaping diabetes risk beyond glucose alone. We begin with evidence linking diabetes to vitamin D deficiency and depression in underserved rural Hispanic populations, highlighting the interplay between nutrition, mental health, and social determinants. We also draw attention to the rising burden of prediabetes in children with obesity, underscoring the urgency of early screening and family-centred prevention.

    Innovation features strongly this month, with emerging research on mild mitochondrial uncouplers that safely enhance energy expenditure. We also spotlight a thought-provoking review from the International Journal of Diabetes and Technology (IJDT) that redefines obesity through the lens of Adiposity-Based Chronic Disease, showcasing how GLP-1 receptor agonists especially oral semaglutide , offer powerful, multisystem, disease-modifying benefits that go far beyond weight loss, reshaping the future of metabolic care.

    We also address diabetes-related complications and comorbidities, with new insights into impaired wound healing, while lifestyle science reinforces practical prevention, highlighting adolescent data that show snack quality, more than how often one snacks, critically influences overall diet quality and long-term cardiometabolic risk.

    Our GEMS Drug Update highlights baxdrostat, a promising new oral therapy for uncontrolled hypertension, while the Recipe of the Month features a fibre-rich, heart-healthy roasted artichoke dish to support metabolic balance. The Picture of the Month offers perspective from public health history, reminding us that prevention principles remain timeless.

    Our GEMS Video of the Month features Dr Jothydev Kesavadev on obesity, offering a clear, stigma-free clinical perspective

    As we step into the year ahead, January GEMS calls for evidence-based choices, compassionate care, and sustained action, because meaningful progress in diabetes prevention begins with informed, consistent practice.

To visit our previous issues, click here

Thanking you once again for the comments and suggestions. If in case you are not interested in receiving this free monthly scientific newsletter, kindly reply with "delete gems" in the subject line to info@jothydev.net

Regards

JDC Diabetes Gems Team
Jothydev's Diabetes and Research Centres
Trivandrum, Attingal and Kochi, Kerala, INDIA
+91 9846040055, +91 9562040055 , +91 9746366655
http://www.jothydev.net

Welcome to the January Issue of GEMS!

As the New Year begins, it brings renewed focus on prevention, reflection, and long-term health. January is a natural moment to reset priorities, and in diabetes care, it reinforces the importance of early action, sustained lifestyle change, and integrated management across the lifespan.
    This edition of GEMS explores the wider forces shaping diabetes risk beyond glucose alone. We begin with evidence ...linking diabetes to vitamin D deficiency and depression in underserved rural Hispanic populations, highlighting the interplay between nutrition, mental health, and social determinants. We also draw attention to the rising burden of prediabetes in children with obesity, underscoring the urgency of early screening and family-centred prevention.

Innovation features strongly this month, with emerging research on mild mitochondrial uncouplers that safely enhance energy expenditure. We also spotlight a thought-provoking review from the International Journal of Diabetes and Technology (IJDT) that redefines obesity through the lens of Adiposity-Based Chronic Disease, showcasing how GLP-1 receptor agonists especially oral semaglutide , offer powerful, multisystem, disease-modifying benefits that go far beyond weight loss, reshaping the future of metabolic care.

We also address diabetes-related complications and comorbidities, with new insights into impaired wound healing, while lifestyle science reinforces practical prevention, highlighting adolescent data that show snack quality, more than how often one snacks, critically influences overall diet quality and long-term cardiometabolic risk.

Our GEMS Drug Update highlights baxdrostat, a promising new oral therapy for uncontrolled hypertension, while the Recipe of the Month features a fibre-rich, heart-healthy roasted artichoke dish to support metabolic balance. The Picture of the Month offers perspective from public health history, reminding us that prevention principles remain timeless.

Our GEMS Video of the Month features Dr Jothydev Kesavadev on obesity, offering a clear, stigma-free clinical perspective

As we step into the year ahead, January GEMS calls for evidence-based choices, compassionate care, and sustained action, because meaningful progress in diabetes prevention begins with informed, consistent practice.
To visit our previous issues, click here
Thanking you once again for the comments and suggestions. If in case you are not interested in receiving this free monthly scientific newsletter, kindly reply with "delete gems" in the subject line to info@jothydev.net
Regards
JDC Diabetes Gems Team
Jothydev's Diabetes and Research Centres
Trivandrum, Attingal and Kochi, Kerala, INDIA
+91 9846040055, +91 9562040055 ,+91 9746366655
http://www.jothydev.net

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Gems picture of the month


This historic image from the 1918 influenza pandemic depicts a nurse wearing a gauze face mask, alongside a public heal..........
public

Gems picture of the month

This historic image from the 1918 influenza pandemic depicts a nurse wearing a gauze face mask, alongside a public heal...........



Diabetes, Vitamin D Deficiency and Depression: Converging Risks in Rural Hispanic Populations
Diabetes is increasingly understood as a condition influenced by multiple inter-related factors beyond glycaemia alone, including......... READ MORE
Diabetes, Vitamin D Deficiency and Depression: Converging Risks in Rural Hispanic Populations

Diabetes, Vitamin D Deficiency and Depression: Converging Risks in Rural Hispanic Populations

Diabetes is increasingly understood as a condition influenced by multiple inter-related factors beyond glycaemia alone, including......... READ MORE

Rapid Rise in Prediabetes Among Children with Obesity: A Growing Silent Epidemic
Prediabetes, once thought to be primarily an adult condition is now emerging as a major pediatric health......... READ MORE
Rapid Rise in Prediabetes Among Children with Obesity: A Growing Silent Epidemic

Rapid Rise in Prediabetes Among Children with Obesity: A Growing Silent Epidemic

Prediabetes, once thought to be primarily an adult condition is now emerging as a major pediatric health........ READ MORE

Making Mitochondria Work Harder: A New Frontier in Obesity Treatment
Obesity remains one of the most pressing global health challenges, increasing the risk of diabetes, cardiovascular disease, cancer, and....... READ MORE
Making Mitochondria Work Harder: A New Frontier in Obesity Treatment

Making Mitochondria Work Harder: A New Frontier in Obesity Treatment

Obesity remains one of the most pressing global health challenges, increasing the risk of diabetes, cardiovascular disease, cancer, and........ READ MORE

Adiposity-Based Chronic Disease (ABCD): Redefining Obesity Care and the Expanding Therapeutic Role of GLP-1 Receptor Agonists
Obesity is increasingly recognised not merely as excess weight, but as a chronic, relapsing, multisystem disease driven by dysfunctional........ READ MORE
Adiposity-Based Chronic Disease (ABCD): Redefining Obesity Care and the Expanding Therapeutic Role of GLP-1 Receptor Agonists

Adiposity-Based Chronic Disease (ABCD): Redefining Obesity Care and the Expanding Therapeutic Role of GLP-1 Receptor Agonists

Obesity is increasingly recognised not merely as excess weight, but as a chronic, relapsing, multisystem disease driven by dysfunctional......... READ MORE

Why Chronic Wounds Refuse to Heal: How Staphylococcus aureus Exploits the Wound Edge
Chronic wounds remain one of the most debilitating and costly complications of diabetes, often progressing silently from delayed healing....... READ MORE
Why Chronic Wounds Refuse to Heal: How Staphylococcus aureus Exploits the Wound Edge

Why Chronic Wounds Refuse to Heal: How Staphylococcus aureus Exploits the Wound Edge

Chronic wounds remain one of the most debilitating and costly complications of diabetes, often progressing silently from delayed healing......... READ MORE

Snacking Patterns, Diet Quality, and Cardiometabolic Risk in Adolescents: Lessons from NHANES (2009–2016)
When it comes to tackling excess body fat especially the harmful kind stored around internal organs most advice focuses....... READ MORE
Snacking Patterns, Diet Quality, and Cardiometabolic Risk in Adolescents: Lessons from NHANES (2009–2016)

Snacking Patterns, Diet Quality, and Cardiometabolic Risk in Adolescents: Lessons from NHANES (2009–2016)

When it comes to tackling excess body fat especially the harmful kind stored around internal organs most advice focuses......... READ MORE

Drug Updates
Baxdrostat is an investigational once-daily oral drug showing promise as a new treatment for uncontrolled and resistant.......... READ MORE
Drug Updates

Drug Updates

Baxdrostat is an investigational once-daily oral drug showing promise as a new treatment for uncontrolled and resistant.......... READ MORE

Lime Spiced Mini Tostada with Guacamole Topper
Healthy eating doesn’t have to be complicated. This vibrant Mediterranean-inspired dish combines fiber-rich.......... READ MORE
Recipe of the Month<br>Roasted Artichokes with Olive Oil and Lemon

Recipe of the Month
Roasted Artichokes with Olive Oil and Lemon

Healthy eating doesn’t have to be complicated. This vibrant Mediterranean-inspired dish combines fiber-rich.......... READ MORE

Diabscreen Kerala, P. Kesavadev Trust, and Jothydev’s Diabetes Hospital, Thiruvananthapuram, in association with........ READ MORE

JDC Updates

Diabscreen Kerala, P. Kesavadev Trust, and Jothydev’s Diabetes Hospital, Thiruvananthapuram, in association with........ READ MORE

The Newsletter team:

Chief Editor : Dr.Jothydev Kesavadev
Managing Editor : Sunitha Jothydev
Editor : Dr.Arun Shankar
Scientific Editor : Gopika Krishnan (2012-2025)
Associate Editor : Anjana Basanth
Sub Editors : M Abdul Khader, Geethu Sanal
Webpage Editor : Athira P B
Founder Editor : Neethu Annie Ajai
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