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Welcome to the December Issue of GEMS!

    As Christmas ushers in a season of warmth, reflection, and renewal, December’s GEMS focuses on protecting the heart, strengthening metabolic resilience, and embracing evidence-based choices for long-term health. The festive season reminds us that care and compassion extend not only to others, but also to ourselves.

    This issue highlights silent yet serious cardiovascular and metabolic risks. We open with a major study on sudden cardiac death in diabetes, underscoring how both type 1 and type 2 diabetes markedly increase the risk of fatal arrhythmias, even in younger individuals. This reinforces the need to recognise diabetes as a condition with immediate cardiac implications, not just long-term metabolic consequences.

    We continue the cardiovascular theme with new evidence showing that reducing smoking is not enough, even light smoking carries significant cardiovascular risk, reaffirming that complete cessation remains the only safe option.

    Innovation features strongly this month. We explore a novel polymer-based transdermal insulin system that could eliminate the need for injections, alongside emerging microbiome research revealing how gut-derived metabolites may protect against insulin resistance by modulating inflammatory pathways. Together, these studies point to more patient-friendly and biologically targeted future therapies.

    Microvascular health is also in focus, with data showing that blood pressure variability plays a key role in diabetic retinopathy risk. Lifestyle science complements this, with long-term evidence confirming that combined improvements in diet quality and physical activity offer the greatest reductions in harmful visceral fat.

    As always, GEMS blends science with everyday living. This month’s Healthy Recipe of the Month, a comforting yet balanced Creamy Cheddar Soup, reflects the season while keeping metabolic health in mind. We then feature our Picture of the Month, capturing academic leadership at ATTD Asia with Dr. Jothydev Kesavadev, alongside research presentations on telemedicine-supported semaglutide titration. Our Video of the Month brings highlights from the 53rd Annual RSSDI Conference at Kochi, showcasing the momentum of India’s diabetes community.

    As the year draws to a close, this Christmas edition of GEMS reminds us that prevention, vigilance, innovation, and compassion must go hand in hand. Protecting the heart and nurturing metabolic health are among the most meaningful gifts we can give this season and beyond.

To visit our previous issues, click here

Thanking you once again for the comments and suggestions. If in case you are not interested in receiving this free monthly scientific newsletter, kindly reply with "delete gems" in the subject line to info@jothydev.net

Regards

JDC Diabetes Gems Team
Jothydev's Diabetes and Research Centres
Trivandrum, Attingal and Kochi, Kerala, INDIA
+91 9846040055, +91 9562040055 , +91 9746366655
http://www.jothydev.net

Welcome to the December Issue of GEMS!

As Christmas ushers in a season of warmth, reflection, and renewal, December’s GEMS focuses on protecting the heart, strengthening metabolic resilience, and embracing evidence-based choices for long-term health. The festive season reminds us that care and compassion extend not only to others, but also to ourselves.
    This issue highlights silent yet serious cardiovascular and metabolic risks. We open with a major study on sudden cardiac ...death in diabetes, underscoring how both type 1 and type 2 diabetes markedly increase the risk of fatal arrhythmias, even in younger individuals. This reinforces the need to recognise diabetes as a condition with immediate cardiac implications, not just long-term metabolic consequences.

We continue the cardiovascular theme with new evidence showing that reducing smoking is not enough, even light smoking carries significant cardiovascular risk, reaffirming that complete cessation remains the only safe option.

Innovation features strongly this month. We explore a novel polymer-based transdermal insulin system that could eliminate the need for injections, alongside emerging microbiome research revealing how gut-derived metabolites may protect against insulin resistance by modulating inflammatory pathways. Together, these studies point to more patient-friendly and biologically targeted future therapies.

Microvascular health is also in focus, with data showing that blood pressure variability plays a key role in diabetic retinopathy risk. Lifestyle science complements this, with long-term evidence confirming that combined improvements in diet quality and physical activity offer the greatest reductions in harmful visceral fat.

As always, GEMS blends science with everyday living. This month’s Healthy Recipe of the Month, a comforting yet balanced Creamy Cheddar Soup, reflects the season while keeping metabolic health in mind. We then feature our Picture of the Month, capturing academic leadership at ATTD Asia with Dr. Jothydev Kesavadev, alongside research presentations on telemedicine-supported semaglutide titration. Our Video of the Month brings highlights from the 53rd Annual RSSDI Conference at Kochi, showcasing the momentum of India’s diabetes community.

As the year draws to a close, this Christmas edition of GEMS reminds us that prevention, vigilance, innovation, and compassion must go hand in hand. Protecting the heart and nurturing metabolic health are among the most meaningful gifts we can give this season and beyond.
To visit our previous issues, click here
Thanking you once again for the comments and suggestions. If in case you are not interested in receiving this free monthly scientific newsletter, kindly reply with "delete gems" in the subject line to info@jothydev.net
Regards
JDC Diabetes Gems Team
Jothydev's Diabetes and Research Centres
Trivandrum, Attingal and Kochi, Kerala, INDIA
+91 9846040055, +91 9562040055 ,+91 9746366655
http://www.jothydev.net

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attd

Gems picture of the month


Dr. Jothydev Kesavadev spoke at ATTD Asia on the evolving links between obesity, fatty liver disease (MASLD/MASH) and..........
attd

Gems picture of the month

Dr. Jothydev Kesavadev spoke at ATTD Asia on the evolving links between obesity, fatty liver disease (MASLD/MASH) and...........



Sudden Cardiac Death in Diabetes: Unmasking a Silent but Devastating Risk
Sudden cardiac death (SCD) is one of the most frightening medical events, a rapid, unexpected loss of heart function that often......... READ MORE
Sudden Cardiac Death in Diabetes: Unmasking a Silent but Devastating Risk

Sudden Cardiac Death in Diabetes: Unmasking a Silent but Devastating Risk

Sudden cardiac death (SCD) is one of the most frightening medical events, a rapid, unexpected loss of heart function that often......... READ MORE

Why “Cutting Down” on Smoking Isn’t Enough: The Real Risk of Even Light Smoking
Smoking has long been known as a major threat to heart and vascular health. But many people hoping to moderate harm......... READ MORE
Why “Cutting Down” on Smoking Isn’t Enough: The Real Risk of Even Light Smoking

Why “Cutting Down” on Smoking Isn’t Enough: The Real Risk of Even Light Smoking

Smoking has long been known as a major threat to heart and vascular health. But many people hoping to moderate harm........ READ MORE

A “Cream for Diabetes”? How a New Polymer Could Let Insulin Slip Through Your Skin: No Needles
Imagine a world where people with diabetes no longer dread the sting of daily insulin injections. Where....... READ MORE
A “Cream for Diabetes”? How a New Polymer Could Let Insulin Slip Through Your Skin: No Needles

A “Cream for Diabetes”? How a New Polymer Could Let Insulin Slip Through Your Skin: No Needles

Imagine a world where people with diabetes no longer dread the sting of daily insulin injections. Where........ READ MORE

When Your Gut Microbes Become Allies: A Surprising Molecule from the Microbiome That Could Combat Insulin Resistance
For years, scientists have studied how an unhealthy diet and obesity trigger chronic, low-grade inflammation that........ READ MORE
When Your Gut Microbes Become Allies: A Surprising Molecule from the Microbiome That Could Combat Insulin Resistance

When Your Gut Microbes Become Allies: A Surprising Molecule from the Microbiome That Could Combat Insulin Resistance

For years, scientists have studied how an unhealthy diet and obesity trigger chronic, low-grade inflammation that......... READ MORE

Blood Pressure Swings & the Eyes: A Hidden Risk for People with Type 2 Diabetes
For years, people with diabetes have been advised to monitor blood sugar and many also know that high blood pressure....... READ MORE
Blood Pressure Swings & the Eyes: A Hidden Risk for People with Type 2 Diabetes

Blood Pressure Swings & the Eyes: A Hidden Risk for People with Type 2 Diabetes

For years, people with diabetes have been advised to monitor blood sugar and many also know that high blood pressure......... READ MORE

Healthy Eating + Movement: The Most Powerful Duo for Controlling Body Fat
When it comes to tackling excess body fat especially the harmful kind stored around internal organs most advice focuses....... READ MORE
Healthy Eating + Movement: The Most Powerful Duo for Controlling Body Fat

Healthy Eating + Movement: The Most Powerful Duo for Controlling Body Fat

When it comes to tackling excess body fat especially the harmful kind stored around internal organs most advice focuses......... READ MORE

Drug Updates
The management of obesity may be on the cusp of another major shift. Data from the TRIUMPH-4 trial show that.......... READ MORE
Drug Updates

Drug Updates

The management of obesity may be on the cusp of another major shift. Data from the TRIUMPH-4 trial show that.......... READ MORE

Lime Spiced Mini Tostada with Guacamole Topper
This rich-tasting soup is packed with flavor, lightened up with reduced-fat ingredients, and balanced with veggies for fiber.......... READ MORE
Recipe of the Month<br>Creamy Cheddar Soup

Recipe of the Month
Creamy Cheddar Soup

This rich-tasting soup is packed with flavor, lightened up with reduced-fat ingredients, and balanced with veggies for fiber.......... READ MORE

Diabscreen Kerala, P. Kesavadev Trust, and Jothydev’s Diabetes Hospital, Thiruvananthapuram, in association with........ READ MORE

JDC Updates

Diabscreen Kerala, P. Kesavadev Trust, and Jothydev’s Diabetes Hospital, Thiruvananthapuram, in association with........ READ MORE

The Newsletter team:

Chief Editor : Dr.Jothydev Kesavadev
Managing Editor : Sunitha Jothydev
Editor : Dr.Arun Shankar
Scientific Editor : Gopika Krishnan (Research Head, JDC Centres)
Sub Editors : Sree Lekshmi R, Anjana Basanth, Geethu Sanal
Webpage Editor : Deepu J S
Founder Editor : Neethu Annie Ajai
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