Welcome to the November Issue of GEMS!

Lighting the Path to Wellness: Diwali, Renewal, and Brighter Lives with Diabetes Awareness
    As we come together to recognise World Diabetes Day 2025, observed globally under the theme “Diabetes Across Life Stages,” this edition of GEMS reflects ... the rapidly expanding science, innovation, and public health priorities reshaping diabetes care today. This theme reminds us that diabetes is not confined to one age group risks begin early, evolve across the lifespan, and require lifelong awareness, prevention, and personalised care.

This month, our featured research spans cutting-edge discoveries to clinical relevance. We begin with a groundbreaking study examining how microplastic ingestion may disrupt pancreatic metabolism, introducing an emerging environmental dimension to metabolic disease risk. The edition continues with a remarkable finding on the intergenerational axis of diabetes: children born to mothers with type 1 diabetes may have epigenetic protection against islet autoimmunity, reshaping long-held assumptions in diabetes genetics and risk prediction.

Further highlighting personalised health, another featured study reveals how diet influences ageing metabolism differently in men and women, supporting a shift toward precision nutrition rather than one-size-fits-all dietary guidance. Mechanistic research also provides new insights into how protein and carbohydrate interactions modify post-meal glucose and hormonal responses, offering refined dietary strategies for glycaemic control.

We also explore the growing public health challenge of lifestyle patterns, with compelling evidence that ultra-processed foods accelerate metabolic dysfunction in young adults, even before diabetes develops, an urgent message for prevention efforts targeting youth and families.

Beyond research, this edition highlights innovation in digital health. The Tidepool–Ōura collaboration marks a major milestone toward more inclusive, real-world metabolic research using wearables, paving the way for deeply personalised diabetes understanding and care.

To support healthier living, our GEMS Healthy Recipe of the Month offers a balanced and culturally adaptable dish: Asian Lentil Sesame Fried Rice, rich in fibre, plant protein, and flavour.

We also take a moment to celebrate community impact. Our Picture of the Month captures the World Diabetes Day Walkathon held by Jothydev’s Diabetes Research Centre in Thiruvananthapuram, a symbolic reminder that awareness, movement, and collective action are vital to reducing diabetes risk. The presence of Shri Shashi Tharoor, Member of Parliament, helped amplify this message across the community. Our Video of the Month, featuring a message from Dr. Jothydev Kesavadev, reinforces the importance of early detection, lifestyle change, and access to care across every stage of life.

As we close this edition, may the insights within inspire awareness, advocacy, and actionable change, because the future of diabetes prevention and care depends not only on science, but on how we apply it at every age and every stage.
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Regards
JDC Diabetes Gems Team
Jothydev's Diabetes and Research Centres
Trivandrum, Attingal and Kochi, Kerala, INDIA
+91 9846040055, +91 9562040055 ,+91 9746366655
http://www.jothydev.net